Australian Centre for Water
and Environmental Biotechnology

AWMC Seminar Program: Pengbo Ding & Mojtaba Morevej

Title: Understanding Contributions of Antidepressants on the Dissemination of Antibiotic Resistance
Presenter: Pengbo Ding

Abstract: The threat from antibiotic resistance is unprecedented, leading to tremendous economic burden and severe risks associated with public health. Substantial attention has been paid to the spread of antibiotic resistance caused by antibiotics, while the contribution of non-antibiotic pharmaceuticals has been largely overlooked so far. Considering the impact of antidepressants on human gut bacteria, further studies investigating potential roles of antidepressants on the spread of antibiotic resistance are encouraged.

This project aims to address whether antidepressants can promote the spread of antibiotic resistance. More importantly, we will reveal the underlying mechanisms by addressing how and why antidepressants can enhance the spread of antibiotic resistance at molecular levels. We will choose most commonly prescribed antidepressants and build up multiple mating model systems (including planktonic bacteria, biofilm and mixed culture matrix). Culture-based experiments in conjugation with fluorescence-based flow cytometry, whole-genome RNA sequencing, and proteomics will be employed in this project. Our findings will offer insights into the contribution of non-antibiotic pharmaceuticals on the dissemination of antibiotic resistance.


Title: Water performance evaluation of infill development
Presenter: Mojtaba Moravej

Abstract:  Securing and protecting urban water resources is a growing challenge due to emerging urbanization growth and climate change. Australian capital cities have infill targets of more than 50% to cope with urbanization growth. Although infill is an opportunity for reshaping cities for the better, its water performance is of a concern due to an increase of impervious surfaces, water demand, and related impacts. How to design and implement technologies for infill development to achieve a higher environmental performance in general and water performance, in particular, is of a question. This research aims to improve our understanding regarding (i) How can water performance of infill be quantified? (ii) Interactions of urban design and technologies to influence water performance in an infill context, and (iii) Long-term impacts of infill on city-scale water performance in an uncertain future caused by climate change, different uptake of technologies and urban design pathways.

This research aims to contribute to the interdisciplinary decision-making process of urban planning by providing a better understanding of water performance and how urban water systems and urban design are linked.

This research contributes to the ‘Water sensitive outcomes for infill developments’ (IRP4) project of the Cooperative Research Centres for Water Sensitive Cities (CRCWSC). IRP4 project covers a wide range of infill impacts including not only water performance but also urban heat, urban space quality, liveability, etc.

Event Details
Date & Time: 
Friday, 13 September 2019
9am - 10am
Venue: AIBN Building 75, Level 1 Seminar Room
  • Pengbo Ding
  • Mojtaba Moravej

Event Contact: