Australian Centre for Water
and Environmental Biotechnology

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Project Dates: 2018 to 2021


Anaerobic oxidation of methane (AOM) by microorganisms is a promising bioprocess for conversion of methane to liquid chemicals. This subproject aims to determine the metabolic pathway of methane and CO2 conversion to VFA and electricity under different conditions.

Recently it was shown that Candidatus ‘Methanoperedens nitroreducens’, an archaeon affiliated with ANME-2d, can couple AOM to nitrate reduction. Metagenomic analysis revealed that the M. nitroreducens harbours genes responsible for the reductive acetyl-CoA pathway and acetyl-CoA synthetase (Acd).

Consistent and reliable bioconversion of methane to acetate is critical for future process and technology development. The feasibility of sustainable acetate production by M. nitroreducens will be further investigated through fundamental metabolic-, and applied membrane bioreactor studies.




  • ARC Australian Laureate Fellowship FL170100086